Mass spectrometry of biomolecules

Identification and quantification of proteins in mixtures
Description: Identification of proteins in complex mixtures and their relative quantification. In-gel or in-solution analysis.
Input: SDS PAGE gel or solution, min. amount of protein: several μg.
Output: List of identified proteins and their relative abundance.
Time: 2-3 days
Approximate price: from 5 000 CZK per sample

Characterization of proteins
Description: Determination of recombinantly expressed or isolated proteins. Characterization of protein modifications.
Input: Protein solution, min. amount: several μg.
Output: Exact molecular weight of proteins and their forms.
Time: 1-2 days
Approximate price: From 5 000 CZK per sample

Characterization of protein-protein interactions
Description: Determination of protein-protein interaction areas and structural changes by hydrogen-deuterium exchange and chemical cross-linking in combination with mass spectrometry.
Input: Protein in solution, min. amount: units of mg.
Output: Description of interaction area and protein structural changes.
Time: 3-7 days
Approximate price: From 10 000 CZK per 1 complex analysis