We pursue curiosity driven basic research in molecular biology emphasizing those aspects that have considerable impact on the population health.
Institute of Biotechnology CAS
New possibilities in fight against pathogenic bacteria
Three international research teams succeded in elucidation of a unique molecular mechanism, which enables bacteria, including pathogens, to maintain the flow of genetic information from DNA to RNA. The discovery leads to new possibilities of development of the much needed antimicrobials against serious pathogens, including the causative agent of tuberculosis. Their discoveries have been published in the journal Nature Communications.
The new laboratory of IBT CAS will focus on the metabolism of healthy ...
In October 2020 a new research group started at the Institute of Biotechnology (IBT) of the Czech Academy of Sciences located at the BIOCEV center. Head of the group, Dr. Katerina Rohlenova, returned to the Czech Republic after a postdoctoral stay in the laboratory of Prof. Peter Carmeliet at the Center for Cancer Biology (VIB-KU Leuven) in Belgium, where she studied metabolism of cells that form blood vessels in tumors. At IBT Katerina teamed-up with Dr. ...
Mitochondria move smoothly through crowded environment
An international team led by researchers from the Institute of Biotechnology of the Czech Academy of Sciences describes a mechanism underlying transport of organelles within cells. The work shows how long-range transport can efficiently work in crowded cellular environments.
Age-dependent response to stroke characterized in mouse model
Cerebral stroke is one of the leading causes of death and long-term disability worldwide. It affects primarily the elderly population and is typically recognized as a disease associated with aging. However, it remains unknown how such an age-dependent vulnerability develops, and what are the underlying mechanisms. ...
PRAHA TV - Guest of the day: Jaroslav Truksa, Iron metabolism of tumor cells
If the cancer cells have little or extremely much iron, they will not be able to cope and die, "describes one of the possible future strategies to fight cancer Mgr. JAROSLAV TRUKSA, Ph.D. D., from the Institute of Biotechnology of the CAS.