We pursue curiosity driven basic research in molecular biology emphasizing those aspects that have considerable impact on the population health.
Institute of Biotechnology CAS
Mitochondria move smoothly through crowded environment
An international team led by researchers from the Institute of Biotechnology of the Czech Academy of Sciences describes a mechanism underlying transport of organelles within cells. The work shows how long-range transport can efficiently work in crowded cellular environments.
Age-dependent response to stroke characterized in mouse model
Cerebral stroke is one of the leading causes of death and long-term disability worldwide. It affects primarily the elderly population and is typically recognized as a disease associated with aging. However, it remains unknown how such an age-dependent vulnerability develops, and what are the underlying mechanisms. ...
Data analysis with program PAIREF leads to more accurate structures of ...
Diffraction methods are capable to determine 3D atomic structures of biomolecules (e.g. proteins and DNA), essential for the design of drugs and biotechnological applications, etc. A new tool PAIREF, developed at CTU in close collaboration with IBT, provides a comprehensive analysis of experimental data resolution that leads to an optimal accuracy of the structures.